30 research outputs found

    What scans we will read: imaging instrumentation trends in clinical oncology

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    Oncological diseases account for a significant portion of the burden on public healthcare systems with associated costs driven primarily by complex and long-lasting therapies. Through the visualization of patient-specific morphology and functional-molecular pathways, cancerous tissue can be detected and characterized non- invasively, so as to provide referring oncologists with essential information to support therapy management decisions. Following the onset of stand-alone anatomical and functional imaging, we witness a push towards integrating molecular image information through various methods, including anato-metabolic imaging (e.g., PET/ CT), advanced MRI, optical or ultrasound imaging. This perspective paper highlights a number of key technological and methodological advances in imaging instrumentation related to anatomical, functional, molecular medicine and hybrid imaging, that is understood as the hardware-based combination of complementary anatomical and molecular imaging. These include novel detector technologies for ionizing radiation used in CT and nuclear medicine imaging, and novel system developments in MRI and optical as well as opto-acoustic imaging. We will also highlight new data processing methods for improved non-invasive tissue characterization. Following a general introduction to the role of imaging in oncology patient management we introduce imaging methods with well-defined clinical applications and potential for clinical translation. For each modality, we report first on the status quo and point to perceived technological and methodological advances in a subsequent status go section. Considering the breadth and dynamics of these developments, this perspective ends with a critical reflection on where the authors, with the majority of them being imaging experts with a background in physics and engineering, believe imaging methods will be in a few years from now. Overall, methodological and technological medical imaging advances are geared towards increased image contrast, the derivation of reproducible quantitative parameters, an increase in volume sensitivity and a reduction in overall examination time. To ensure full translation to the clinic, this progress in technologies and instrumentation is complemented by progress in relevant acquisition and image-processing protocols and improved data analysis. To this end, we should accept diagnostic images as “data”, and – through the wider adoption of advanced analysis, including machine learning approaches and a “big data” concept – move to the next stage of non-invasive tumor phenotyping. The scans we will be reading in 10 years from now will likely be composed of highly diverse multi- dimensional data from multiple sources, which mandate the use of advanced and interactive visualization and analysis platforms powered by Artificial Intelligence (AI) for real-time data handling by cross-specialty clinical experts with a domain knowledge that will need to go beyond that of plain imaging

    Artificial intelligence assistants and risk: framing a connectivity risk narrative

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    Our social relations are changing, we are now not just talking to each other, but we are now also talking to artificial intelligence (AI) assistants. We claim AI assistants present a new form of digital connectivity risk and a key aspect of this risk phenomenon relates to user risk awareness (or lack of) regarding AI assistant functionality. AI assistants present a significant societal risk phenomenon amplified by the global scale of the products and the increasing use in healthcare, education, business, and service industry. However, there appears to be little research concerning the need to not only understand the risks of AI assistant technologies but also how to frame and communicate the risks to users. How can users assess the risks without fully understanding the complexity of the technology? This is a challenging and unwelcome scenario. AI assistant technologies consists of a complex eco-system and demands explicit and precise communication in terms of communicating and contextualising the new digital risk phenomenon. The paper then agues for the need to examine how to best to explain and support both domestic and commercial user risk awareness regarding AI assistants. To this end, we propose the method of creating a risk narrative which is focused on temporal points of changing societal connectivity and contextualised in terms of risk. We claim the connectivity risk narrative provides an effective medium in capturing, communicating, and contextualising the risks of AI assistants in a medium that can support explainability as a risk mitigation mechanism
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